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July 24, 2006 — Like Viagra before it, a drug once studied to treat heart problems may help treat sexual dysfunction. But this time it’s being tested exclusively for women. A new study shows that a modified version of the experimental heart drug Candoxatril was effective at increasing blood flow to the vagina in animal tests. If further research confirms these results in humans, the drug may be used to treat female sexual arousal disorder (FSAD). Researchers say an estimated 40% of women suffer from FSAD or other forms of sexual dysfuction, such as low libido or pain during intercourse. Candoxatril went into clinical trials in the 1990s as a heart failureheart failure ed pills How the Drug WorksCandoxatril is one of several compounds that targets levels of vasoactive intestinal peptide (VIP), which controls blood flow to the vagina. Researchers say decreased blood flow to the vagina is thought to be a key factor in female sexual arousal disorder. An enzyme called NEP degrades VIP in the body, and Candoxatril works by blocking NEP. In a new study, published in the Journal of Medicinal Chemistry, erectile dysfunction meds In animal tests, researchers at Pfizer Global Research and Development in the U.K., found the new compound effectively blocked NEP, took effect quickly, and the effect lasted for a cheap uk viagra They say the results suggest that the drug might have similar effects in humans, but further research is needed. |
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